MC-Transaction on Biotechnology, 2011, Vol. 3, No. 1, e1
Submerged Liquid Culture of Cordyceps militaris
Evan Chen, Ji-Yuang Liang, Chien-Wei Cheng*
Department Biotechnology, School of Health Technology, Ming-Chuan University (Taoyuan, Taiwan, R.O.C.)
Corresponding author: Chien-wei Cheng [ochien@gmail.com ]
Received 7 March 2011/Accepted 11 March 2011/Online published 29 March 2011
Abstract
There are more than one hundred species of the fungi belonging to the entomogenous Cordyceps have been found. Among the entomofungus, except for the famous Chinese medicinal fungus C. sinensis, C. militaris and C. myrmecophila were the most studied species. Because C. sinensis is not able to be cultured, a substituted entomofungus which can be mass-production is desired. It shows in the literatures that the composition of the functional ingredients from C. militaris is similar with C. sinensis. However, the mycelia of C. militaris can be mass-produced by submerged bioreactors. C. militaris attracts abundant efforts of research during the past decades. Previous studies in C. militaris have been focused on the analysis of the functional ingredients and health promotion ability tests, as well as the optimization of the processing parameters. Although C. militaris can be produced in a large scale, unceasing improvement and optimization to the incubation condition is necessary.This communication is a review to the development in the submerged fermentation of C. militaris.
Keyword: Cordyceps militaris, Cordyceps sinensis, entomofungus, cordycepin,submerged, fermentation
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