MC-TB 2013 Vol 5, No.1, pp 20-29
Effects of Reactive Oxygen Species from Blue Light-Excited Flavin Mononucleotide
on Inhibiting of Hepato Cell (Huh-7)
Chi-Ming Chiu, Yu-Chen Hung, and Ji-Yuan Liang*
Department of Biotechnology, School of Health Technology, Ming-Chuan University,
(Taoyuan, Taiwan, R.O.C.)
Corresponding author: Ji-Yuan Liang [liang121@mail.mcu.edu.tw ]
Received 19 Oct 2013/Accepted 29 Oct 2013/Online published 5 Nov 2013
Abstract
Flavin mononucleotide is sensitive to blue light. Various compounds may be derived
from flavin mononucleotide after illumination. This study was working on the effects
of reactive oxygen specie from light-excited flavin mononucleotide on the reduction
percentage of hepato cell (Huh-7) growth. The 35-60% reduction percentage of
hepato cell (Huh-7) was occurred by light-excited flavin mononucleotide reaction.
Flavin mononucleotide photochemistry may be a simple and safe technology for
photodynamic therapy.
|
|